27-28 September, 2018

Boston, USA

Post-Conference Workshop
Friday, 28 September, 2018

15.00 - 17.00
Translation from Animal to Human: A Workshop on Strategies & Applications
Workshop Leader: Alexandros Makriyannis, Chemistry & Chemical Biology Director, The Center for Drug Discovery Northeastern University

 

This interactive workshop session will delve deep into the challenges associated with the lack of predictability and robustness of preclinical models. Join this session to increase your rate of success in clinical development by understanding, discussing and overcoming the translational hurdles to safely and effectively take first in class non-opioid pain therapies from bench to bedside.

  • There are different types of pain: Delving into the different types of pain and pain pathways
  • There are different types of pain models; Discussing advances and challenges for clinical translation
  • How to optimize translation into clinic by exploring the “low hanging fruit” of past and current pain research
  • Endocannabinoid system modulation provides successful approaches for addressing pain issues: Case study explored
  • Review and discuss the case study by reflecting on the initial efforts through direct activation of both CB1 and CB2
    receptors and why the current approaches involve indirect activation of both receptors

Alexandros Makriyannis, Chemistry & Chemical Biology Director, The Center for Drug Discovery Northeastern University